Metabolites from Wild Potato Inhibit Virulence Factors of the Soft Rot and Blackleg Pathogen <i>Pectobacterium brasiliense</i>

Potato (Solanum tuberosum L.) is the primary vegetable crop consumed worldwide and largely affected by bacterial pathogens that can cause soft rot blackleg disease. Recently, resistance to these diseases has been identified in wild potato S. chacoense, mechanism of unknown. Here, it was hypothesized chacoense stems or tubers have unique chemistry confers pathogen Pectobacterium brasiliense through bactericidal, bacteriostatic, antivirulence activity. Stem tuber metabolite extracts were collected from tested for effects on multiplication rates, activity expression known exoenzymes virulence genes using as a comparative control. Comparatively, did not affect rate; however, they reduce pectinase, cellulase, protease activities. The chemical profiled bioassay-guided fractionation, nontargeted metabolomics comparison performed. data showed selected alkaloids, phenolic amines, phenols, peptides are integrative sources against bacteria. [Formula: see text] Copyright © 2021 Author(s). This an open access article distributed under CC BY-NC-ND 4.0 International license .